Professional and Busi

ness Chances.

Under this head we shall insert free of charge an advertisement occupying not more than four lines, which is equal to about twenty-eight words, to any one whose name is on the subscription list of the SUM-MARY. For additional words, or if more than one insertion is desired, cash, at the rate of Two Cents per word, is required. If letters are to be sent in care of this office an extra fee of 25 cents must accompany the order. Instruments, Preparations, etc., advertised under this heading at double the above rates.

READ-Wanted and For Sale Ads Inserted in this column for 2 Cents per Word.

AN NY physician wishing a good practice in Providence will learn of something greatly to his interest by writing for particulars to "Physician," Box 378, Providence, R. I.

MEDICAL AGENTS wanted for "Medical Consultation Book." Just issued. Dr. G. P. Hachenberg, Austin, Texas.

SPECIAL OFFER to Physicians and Surgeons.-150

No. 6 XXX high-cut white envelopes printed to order and postpaid, 50 cents; note heads do. W. J. Kafroth, printer, Talmage, Lancaster Co., Pa. Samples free.

200 Medical Practices for sale. Lists mailed tree.

Practices and drug stores bought and sold. Assistants and partners provided. Address, THE MEDICAL ECHO, Lynn, Mass.

-THE

Detroit Metric Granule Co. Manufacturers SOLUBLE, Dosimetric Ganules.

In use in nearly every State in the Union. Progressive physicians by the thousands are adopting this new, but reliable, effective and simple mode of administering medicines.

Alkaloids, Glucosides,

Metaloids, Concentrations.

Catalogue and price-list of over 300 different kinds sent on application. Samples free. When ordering samples state kind preferred.

Address,

DETROIT METRIC GRANULE CO.,

DETROIT. MICH.

Constipation.

Pavara Pills produce a prompt, painless and natural evacuation of the bowels, without the usual sequence of constipation: and they will not, under any conditions, interfere in the slightest degree with other medical treatment.

Formula printed on outside label. For constipation during preg nancy, these pills are a perfect remedy, A large bottle (150 pills) will be mailed to any physician, for trial, on receipt of 25 cents in postage stamps.

Prepared by C. L. TOPLIFF, New York. P. O. Box 991.-Depot, 115 Fulton Street.

Brief Notes.

The Superinintendent and Surgeon in Charge of St. Louis City Hospital, Dr. H. Marks, says that Cod-Liver Glycerine is now used in that institution. Its power to mix uniformly in all proportions, in any prescription, or to mix with water or spirits without separating on standing, renders it the most desirable reconstructive in the convalescent period of difficult surgical cases, or acute diseases attended with emaciation, while its digestive properties insures its therapeutic action..

S. E. Morrill, M. D., who has written a treatise of Practical Instructions in the Medical and Surgical Uses of Electricity," writes: "I am treating cancers successfully, and they cannot be cured save with the Kidder Battery."

As a gentle hint to any of our subscribers in arrears we quote the following trom the pen of a Georgia editor, who evidently had strong feelings on the subject: "The wind bloweth, the farmer soweth, the subscriber oweth, and the Lord knoweth that we are in need of our dues. So come arunnin' ere we go a gunnin; we're not funnin'; this thing of dunnin' gives us the blues."

ONE DOLLAR PER ANNUM, IN ADVANCE.

VOL. XV.

SINGLE COPIES, TEN CENTS

No. 6

Will someone write a good book on symptomatology which will be a reliable repository of facts, conclusions and correct reasoning? As far as the writer's information goes, no work devoted exclusively to the subject has been published in the interest of the regular profession. Therefore, let those whose knowledge, clinical experience and opportunities fit them for the enterprise bestir themselves, and thereby add to their fame and usefulness.

Signs of disease may be taken up alphabetically, or arranged under chapterssymptoms being defined, their numerous indications plainly pointed out and differentiated. . In this way subjects as " Pain,"

"Cough," "Vertigo," "Constipation," etc., would receive thorough elucidation, the author telling all that is meant, emphasizing what it more particularly signifies, classifying and showing its importance to diagnosis by association with certain other symptoms.

This is merely a hint, which it is hoped will arrest the attention of the reader, who may see that the field is a fertile one and promises a rich harvest to reward honest ambition.

Referring to another matter, is it not about time the profession received a con- . tribution on diagnosis, different and better adapted to its present needs than the once excellent and time-honored treatises that adorn our shelves? Great helpers they have been, but in their present form they have, in a great measure, outlived their day of usefulness. Comprehensiveness and more attention to details are demanded by the exacting needs of professional life. We must have better classification; throw the light of investigation into the dark places, of which there are many that hitherto have received very scant attention; make everything complete as may be, so

that the busy practitioner or student perplexed about a multitude of things, may find the aid he seeks; his author's exemplifications are a veritable gold mine.

No one needs the friendly help of such a treatise so much as the ordinary, dailygoing, general practitioner. He finds popular works mostly inadequate. Give him something so full, plain and rational, and withal concise, that the few minutes taken from the constant go may be really utilized in behalf of doctor and patient, and not wasted in perusing incomprehensible and meaningless details.

SALICYLIC ACID-IMPORTANT.

It is well known that salicylic acid, if given in doses large and frequent enough, subdues very quickly the pains-and in most cases also the whole attack-of acute articular rheumatism. But many physicians do not employ the drug as it ought to be done, because of its dangerous effects on the circulation, and because of its very annoying gastric disturbances, which are apt to develop when large doses of the acid are administered. But why is it that other physicians praise the remedy so highly, and consider it free from danger and easily borne by the stomach?

It is not so difficult to throw light on the subject. Salicylic acid may be bought at prices varying from 30 cents to $2.50 per pound. The purer the drug the dearer is it, but the freer of all deleterious by-effects. Recently we were called to a patient who suffered from a severe attack of acute rheumatism. He told us he would suffer the pain rather than the gastric and other annoyances of salicylic acid. After explanation he agreed to let us make one more trial. We prescribed for him the pure acid, and within twelve hours his pain had disappeared and his stomach evinced no disturbance whatever!

Physicians would do well, therefore, to

insist upon their apothecaries purchasing the purest acid, and the gratitude of their patients will soon reward them.

EUPHORBIA PILULIFERA.

We concur with others in the opinion that the value of euphorbia pilulifera in a large percentage of what are recognized as asthmatic cases is not generally known to the profession. We would suggest that this remedy be given a trial by those of our readers who have an opportunity to do so, and report their results. Iodide of potassium may be combined with it when indicated. Euphorbia should, however, be administered with caution when the kidneys are in a diseased condition, as the coloring matter affects these organs.

Euphorbia pilulifera is also useful in bronchitis of asthmatic type. Dr. McCall, of Hamersville, O., writes us that recently he had a case of measles, a married lady in the fifth month of pregnancy, with bronchial complication of asthmatic character; breathing so painful and oppressed that at night she was unable to occupy other than a sitting position, and all ordinary means failed to afford relief. Euphor bia was given with the effect of relieving tightness and same of weight and procuring rest and sleep. The result was all that could be desired, and no subsequent difficulty was experienced. The specific tincture was used, a drachm of which was diffused in about four fluid ounces of water, and a teaspoonful given every half hour till relieved, and then at longer intervals.

Look this copy of the SUMMARY over if not already a subscriber, and consider whether you should not be willing to patronize such a journal that furnishes you with short, practical papers from the best sources-successful modes of treatment, and not abstruse pathological theories—a national journal devoted to practical medicine only, and the organ of nothing save the medical profession.

New Remedies.

In the following we will mention the most import ant new remedies that have been discovered of late, selecting only those whose therapeutical value has been proved, and the administration of which is followed by definite results-therefore, only those that may be relied upon. In a general way their chemical nature, and the sources from which they are derived, as well as the method of manufacture, when known, will also be referred to; their doses will be given, and any obnoxious or dangerous by-effects will be brought prominently to the notice of the reader. Many of the new drugs are so-called proprietary medicines-i. e., their discoverers have secured to themselves the ownership, and in some the exact mode of manufacture is kept secret. For these very reasons we have been the more careful to enumerate only the drugs of recognized value to the profession, such as are being employed by the most eminent members of the fraternity here and abroad, so that the reader may place the fullest confidence in every statement made in these lines.

Pyridinum. — Antispasmodic, especially in asthma.

Many organic nitrogenous substances on dry distillation produce pyridin-bases; and they develop, therefore, for instance, in tobacco smoke. It is obtained mainly from coal-tar.

Pyridinum nitricum and sulphuricum are used; the first forms long, colorless needles, and is easily soluble in water-C5H5N HNO3; the latter, (C5H5N)2SO4H2, is crystaline, and soluble in water and alcohol.

According to See, the effect of asthmacigarettes is due to Pyridinum, but its best and almost instantaneous effect is observed only in nervous asthma. In heart disease and in cases of great debility the remedy should not be administered.

MODE OF USING PYRIDINUM.-From onehalf to one drachm of the drug is spread on a plate, and then placed somewhere in the room of the person suffering from asthma. At a temperature of from 65 to 70 deg. the quantity mentioned evaporates in about an hour. The attack generally ceases at once. It is, however, a palliative and not a cure; still of great value, because of the promptness with which relief is obtained.

So rapid is the absorption of the drug, when inhaled, that within a few minutes after, pyridinum can be demonstrated in the urlne.

Internally it has thus far been given (employing the nitrate and sulphate) only to animals; in the human being it had best be used internally only with the greatest

Diabetine (SCHERING).-A substitute for sugar in diabetes.

Glycerin, and later saccharin, were used as a substitute for sugar, which is so harmful in diabetes. But saccharine has not answered its purpose, as it gradually produces in the patient an insurmountable disgust and, besides, a peculiar, annoying scratching sensation in the throat.

It has long been known that cane sugar consists of dextrose and diabetine. The former is the hurtful substance, which causes much injury in diabetes, and is also harmful in persons with a tendency to corpulency. But the diabetine of fruit sugar does not increase the amount of sugar in the urine, and as it is completely oxydized in the system, it serves to build up the body.

There was but one objection to its use heretofore, but this objection was a most powerful one, viz., its high price; until very recently the pound cost $110 to $130. Schering, in Germany, (Schering & Glatz, 55 Maiden Lane, New York, are their representatives in our country,) has at last succeeded in discovering a new method of manufacture, which enables him to offer the valuable drug and sugar-substitute, diabetine, for $2.00 per lb., a comparatively very low price, if we consider the small quantity needed for sweetening purposes.

Schering's Diabetine is a dry crystaline, easily soluble substance; is chemically pure and intensely sweet.

Another important point in this diabetine is its nutritive value, while saccharine, besides being adulterated in nine cases out